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Tyler Jacks

David H. Koch Professor of Biology

Director, Koch Institute for Integrative Cancer Research 

David H. Koch Professor of Biology

Director, Koch Institute for Integrative Cancer Research 

Tyler Jacks
David H. Koch Professor of Biology
Daniel K. Ludwig Professor for Cancer Research
Director, Koch Institute for Integrative Cancer Research
Howard Hughes Medical Institute investigator
Associate member, Broad Institute

The son of an MIT professor, Tyler Jacks followed a circuitous educational path before joining the MIT faculty in 1992. He is an award-winning pioneer in using gene-targeting technology in mice to study human cancer types. A former director of the Center for Cancer Research, he now heads the David H. Koch Institute for Integrative Cancer Research, a groundbreaking cancer-research facility that unites scientists and engineers in the development of new treatment options.

Highlights of this interview include:

  • Early work with Harold Varmus at the University of California, San Francisco and Robert Weinberg at the Whitehead Institute.
  • The effects of mutations of tumor suppressor genes on tumor development, normal development, and other cellular processes.
  • Important contributions made by MIT researchers to the understanding and treatment of cancer.
  • Promising collaborative research at MIT that may change cancer treatment dramatically during the next generation.
  • Advantages of researching in the MIT environment.

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